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The reason why tests for COVID, RSV, and flu come back negative in patients who have mystery illnesses is explained here

Currently, there are many sick people in the US who have fevers, coughs, and sore throats. The flu and cold season have arrived early, which has surprised many people.
A COVID and flu test can help you get access to antiviral medications if you have a fever.
The Centers for Disease Control and Prevention Director Rochelle Walensky stressed that multiple respiratory illnesses are here early this holiday season, challenging overburdened ...
...hospitals across the country. She added that the cold weather, the gathering indoors, and all of those things are good for respiratory viruses, and bad for symptoms.
Since Thanksgiving, there have been an increase in flu cases and hospitalizations, but some people are complaining that while they are still very ill, they are testing negative for the flu, RSV, or COVID.
The author Cora Harrington described the virus she contracted as one of the strangest illnesses she has ever experienced on Twitter. The virus left her practically unconscious for a couple of days.
Many different viruses, not just the flu and COVID, are reportedly having a real "party" this year, according to doctors from at least three continents.
Furthermore, people shouldn't rule out the possibility that an early COVID, RSV, or flu test may not return a positive result. If you have a fever right now, take this into account.
Dr. Roy Gulick, director of infectious diseases at New York-Presbyterian and Weill Cornell Medicine, told Insider that symptoms like fever, muscle aches, coughing, and headaches would be frequent.
The distinction between the flu and COVID is virtually nonexistent.
Vaccinations can still be received, according to Walensky.
However, Gulick noted that other possibilities include older coronaviruses, an adenovirus, and, of course, the common cold. All of these have the potential to result in an upper respiratory infection.
Gulick opined that most people probably don't need to be aware of their possessions.
They will simply have to deal with the illness before recovering with supportive care.
Even though there isn't currently a cure or vaccine for viral diseases like RSV, Gulick said that people can take steps to prevent getting the flu or COVID ... getting vaccinated, getting their immunity up, and using antiviral medications like Paxlovid for COVID and Tamiflu for the flu when necessary.